Detect cardiotoxicity earlier without labels and without disrupting your cells

Many drug candidates fail at a late stage due to cardiotoxicity, which often become evident only after extensive and costly development.

Digital Holographic Microscopy (DHM®) provides a direct, label-free way to quantify cardiomyocyte beating, enabling earlier and non-invasive detection of drug induced dysfunction.

Find out more in our latest newsletter.
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Our latest newsletter introduces the Compact-DHM®, a miniature module that brings the power of quantitative holographic imaging into custom instruments. Built on the same proven DHM® technology as our standard systems, it enables a wide range of applications — from cell viability and 4D tracking to microfluidics and morphology analysis.

The Compact-DHM® has already seen its first integration for in-situ monitoring of micro-plankton at 200 m depth, showcasing its versatility in even the most challenging environments.

Find more in our newsletter.

Park Systems Corp. has acquired Lyncée Tec SA. In the words of  Dr. Sang-il Park, Founder and CEO of Park Systems, “Park Systems will integrate Lyncée Tec’s DHM technology into our Atomic Force Microscope (AFM) platform and build a fully automated DHM® system, targeting various semiconductor applications, especially advanced packaging.”

Lyncée management, Dr. Yves Emery, Founder and CEO and Dr. Etienne Cuche, Founder and CTO are excited to become part of the Park Systems family, and to produce even more efficient and disruptive DHM®.

There will be no change in current activities and support of installed systems.

Find out more in our press release

A recent publication demonstrates how DHM measures the metabolic activity of breast cancer cells, and how this parameter correlates with cancer malignancy.

Find more in our newsletter.

Lyncée Tec NEW stroboscopic module has been used to investigate Band Gap High-Q resonances of a Phononic Crystal.

This application demonstrates simultaneous extremely high resolution of:

  • frequency (1 ppb)
  • pixel density (1 and 4 MPx)
  • vertical displacements (< 1 picometer)

Learn more about it !

Samples courtesy: Prof. Dr. Albert Schliesser, and Dr Eric Langman, Niels Bohr Institute, Copenhagen University, Denmark, and QFactory ApS

Our customer Silicon Austria Labs (SAL) received the new DHM as the winning prize of Lyncee Challenge 2022! By integrating a motorized goniometer on their new DHM, they have fully automated the measurement of the micromirror:

  • Resonant frequency
  • Maximum deflection angle
  • Phase shift at resonance
  • Dynamic deformation over its full deflection angle range
  • Rotation axis

Validate efficiently your simulations against experiment data and improve your MEMS design! Read more.

With experiments run in parallel our Digital Holographic Microscope (DHM®) will:

  • increase your throughput
  • find active compounds faster
  • improve your drug discovery process

Find out more in our latest newsletter.

Silicon Austria Labs (SAL) won Lyncée Tec Challenge 2022 for their outstanding and innovative demonstration of measuring dynamic deformations of MEMS mirrors at all scanning angles using DHM’s unique full field vibration mode shape analysis. Their prize is a DHM Holographic MEMS Analyzer! Congratulations to the WINNER and to all participants!

Read our newsletter and check out the 5 best applications!

TWO new opportunities at Lyncée Tec. Come and join an innovative team !

Our first life science DHM was delivered 16 years ago.

The innovative data generated by the main user, Dr Pascal Jourdain, with his microscope triggered major contributions to the new research field of OPTICAL electrophysiology.

Find out more in our latest newsletter

We are very happy to officially launch Lyncée Tec Challenge 2022! The goal of the challenge is to encourage exploration of the potential of high laterally resolved vibration analysis with DHM and to reward the best application a DHM Holographic MEMS Analyzer! Register before July 30th 2022 and WIN a DHM! More details please visit https://challenge.lynceetec.com/

Congratulations to our DHM’s users at Silicon Austria Labs who present their latest achievement in SPIE Photonics Europe 2022. Their reported methods enable continuous dynamic deformation measurement of MEMS micromirror at any scan angle.

Find out more in our application page

DHM® up to 100’000 fps confirms the mechanism of sonogenetics

In a seminal publication, the group of James Friend at UCSD discovers the mechanism of ultrasound causing ion channel activation underpinning sonogenetics. For this application they use Lyncée Tec High-speed DHM®

Find our more in our latest newsletter

During the COVID-19 pandemic travel restriction period, trees were planted for DHM® purchased through remote demonstrations

Our users’ forest has over 3000 trees

Lyncée is pleased to extend this action beyond the pandemic in the hope of limiting the ecological footprint of its activity

Read our newsletter and book a remote demo

Digital Holographic Microscopy (DHM®) quantitative phase images record the morphology (shape) and content (hemoglobin content) of Red Blood Cells and provide an important clinical readout on the health status of RBC without label as demonstrated in this latest publication in the International Journal of Molecular Sciences.

Find out more

A nice publication in the Journal of Physics Photonics
retracing Lyncée path from pioneer work in 1999 to revolutionary and matured applications in 2021
in the field of optical metrology.

With DHM® by Lyncée, just measure and discover!

Learn more about it …

Transient characterization by Digital Holography Microscope (DHM®) encompasses:
  • Excitation signal: User-programmable waveform shapes
  • Time Domain: Mega-data-points resolution 4D topography time-sequences
  • Frequency Domain: Mega-pixels vibration maps, bandwidth up to 200 MHz.
  • Environmental control: Temperature, pressure, humidity, gas, liquid, etc.
Applications: cMUT, pMUT, inertial sensors, optical and mechanical switches, MEMS microphones, etc. (Learn more)

PhD on DHM® 4D tracking of motile phytoplankton

Workplace: Lyncée Tec SA Lausanne, Switzerland
Academic affiliation: Environmental Microfluidics Group in the Institute of Environmental Engineering, ETH Zurich
   
Learn more about this position
enabling you to interact with 14 leading European research groups and companies
of the Innovative Training Network (ITN) PHYMOT (PHYsics of microbial MOTility)

A new seminal publication reports real-time 4D topography measurements with our Digital Holography Microscopes (DHM®) SIMULTANEOUSLY to laser processing.

Congratulations to Professor Arri Priimägi and his team at Tampere University.
(Learn more here)

Explore cell health and physiopathological processes with the EVOLUTIVE DHM® T series by Lyncée Tec

Find the model which fits your end-of-year budget: enquire for best prices
Launch offer: for an order placed before 31.12.2020
Get high-value Cells Analysis Tool software for FREE

(Learn more here)